See for a book written by Erik Huelsmann and Chris Travers on LedgerSMB. LedgerSMB also comes with an extensive manual in the doc/ directory.

Or watch the quickstart video:

This is really a quickstart:

  • creating a new database via the browser, using
  • logging in to the new database
  • setting some parameters, populating the database with some data
  • creating new customer
  • and the main part: issuing the first invoice :)